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PEX14 Polyclonal Antibody, 100ul 3D Culture This protein functions as a

SKU: 64196094864

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PEX14 Polyclonal Antibody, 100ul 3D Culture This protein functions as aThis gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.

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Description

This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers

Contains 1 Myb-like domain

The gene was shown to be expressed primarily in brain and liver| and at a lower level in heart and stomach

Plays an essential role in embryonic vascularization| tumor angiogenesis and pathophysiology of ischemic disease

PEX14 Polyclonal Antibody, 100ul 3D Culture This protein functions as aThis gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.

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