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Epsin 1 Polyclonal Antibody, 20ul Serological Pipets POLQ acts as an inhibitor

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Epsin 1 Polyclonal Antibody, 20ul Serological Pipets POLQ acts as an inhibitorEPN1 encodes a member of the epsin protein family. The encoded protein (epsin 1) binds clathrin and is involved in the endocytosis of clathrin coated vesicles. Loss of function of EPN1 is associated with reduced tumor growth and progression in certain cancer types.

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Description

POLQ acts as an inhibitor of homology-recombination repair (HR) pathway by limiting RAD51 accumulation at resected ends (PubMed: 25642963)

The encoded protease has a specificity similar to that of chymotrypsin C

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a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain

Epsin 1 Polyclonal Antibody, 20ul Serological Pipets POLQ acts as an inhibitorEPN1 encodes a member of the epsin protein family. The encoded protein (epsin 1) binds clathrin and is involved in the endocytosis of clathrin coated vesicles. Loss of function of EPN1 is associated with reduced tumor growth and progression in certain cancer types.

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