LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges the encoded protein disrupts BTK-mediated

the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription

Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy

and it is found in the mitochondrial intermembrane space in healthy cells

Variations in this protein's sequence have been implicated in Alzheimer's disease

LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges the encoded protein disrupts BTK-mediatedThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative