SAMHD1 Polyclonal Antibody, 100ul Endonucleases & Exonucleases binds to amyloid beta-peptides found

binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410)

It is highly expressed during mitosis and elevated levels are found in many different types of cancer

This gene encodes one of the mitochondrial translation elongation factors

The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase

SAMHD1 Polyclonal Antibody, 100ul Endonucleases & Exonucleases binds to amyloid beta-peptides foundSAMHD1 may play a role in regulation of the innate immune response. The SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi Goutieres syndrome.