IκB- Epsilon(Phospho Ser22) Polyclonal Antibody, 20ul Subcellular Fractions AKT serine/threonine kinase 2 is

AKT serine/threonine kinase 2 is a general protein kinase capable of phophorylating several known proteins

The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways

It is a enzyme located in the mitochondrial outer membrane

Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo

IκB- Epsilon(Phospho Ser22) Polyclonal Antibody, 20ul Subcellular Fractions AKT serine/threonine kinase 2 isThe protein encoded by this gene binds to components of NF kappa B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF kappa B by making it available to translocate to the nucleus.