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EI2BE Polyclonal Antibody, 100ul Pasteur Pipets likely interacting with roundabout homolog

SKU: 63330269147

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EI2BE Polyclonal Antibody, 100ul Pasteur Pipets likely interacting with roundabout homologThis gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

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Description

likely interacting with roundabout homolog receptors to effect cell migration

Mutations in this gene cause CD59 deficiency

The mediator complex subunit 8 may also function in ubiquitin ligation and protein degradation

While the interaction with CBL is apparently mediated via the hydrophobic region of this domain

EI2BE Polyclonal Antibody, 100ul Pasteur Pipets likely interacting with roundabout homologThis gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

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