11 Beta-HSD1 Polyclonal Antibody, 100ul[BT-AP00001] Enzyme Activity Assays Protein structure suggests a role

Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels

May function as scaffolding or signaling protein

This gene encodes a member of the suppressor of hairless protein family

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11 Beta-HSD1 Polyclonal Antibody, 100ul[BT-AP00001] Enzyme Activity Assays Protein structure suggests a roleHydroxysteroid 11 beta dehydrogenase 1 encoded by HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in HSD11B1 has been associated with obesity and insulin resistance in children. Mutations in