TAB2 Monoclonal Antibody, 100ul Cell Culture Plates It is specifically localized to

It is specifically localized to the sarcoplasmic reticulum and nuclear membrane

Several transcript variants encoding different isoforms have been found for this gene

delta and rho

which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit

TAB2 Monoclonal Antibody, 100ul Cell Culture Plates It is specifically localized toThe protein encoded by this gene is an activator of MAP3K7 TAK1, which is required for for the IL 1 induced activation of nuclear factor kappaB and MAPK8 JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11 RANKl through the activation of the receptor activator of NF