ACK Polyclonal Antibody, 50ul Glassware Binds to and inhibits cyclin-dependent

Binds to and inhibits cyclin-dependent kinase activity| preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression

This gene is expressed in different carcinomas

This PTP possesses an extracellular region

This gene is ubiquitously expressed in adult tissues

ACK Polyclonal Antibody, 50ul Glassware Binds to and inhibits cyclin-dependentTNK2 encodes a tyrosine kinase that binds Cdc42Hs in its GTP bound form and inhibits both the intrinsic and GTPase activating protein (GAP) stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C terminal to an SH3 domain. The tyrosine kinase non receptor 2 may be involved in a regulatory mechanism that sustains the GTP bound active form of Cdc43Hs and which is directly linked to a tyrosine