MMP7 (Cleaved-Tyr95) Rabbit Polyclonal Antibody, 50ul Drying & Desiccation The RUN domain is involved

The RUN domain is involved in Ras-like GTPase signaling| and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif

most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases

The protein has also been found to have antimicrobial activity against bacteria| viruses and fungi

it fails to promote ODC degradation in vitro

MMP7 (Cleaved-Tyr95) Rabbit Polyclonal Antibody, 50ul Drying & Desiccation The RUN domain is involvedCatalytic activity: Cleavage of 14 Ala Leu 15 and 16 Tyr Leu 17 in B chain of insulin. No action on collagen types I II IV V. Cleaves gelatin chain alpha 2(I) > alpha 1(I). cofactor: Binds 2 calcium ions per subunit. cofactor: Binds 2 zinc ions per subunit. The conserved cysteine present in the cysteine switch motif binds the catalytic zinc ion thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation peptide