BACE Polyclonal Antibody, 50ul[BT-AP06646] Human Genome Knockout Libraries More than 80 different mutations

More than 80 different mutations in this gene have been reported| most mutations are related to amyloid deposition

but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action

They are stable secretory proteins expressed in gastrointestinal mucosa

including bladder cancer

BACE Polyclonal Antibody, 50ul[BT-AP06646] Human Genome Knockout Libraries More than 80 different mutationsThis gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which