CI072 Rabbit Polyclonal Antibody, 50ul Nucleic Acid Amplification IRF1 has been shown to

IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion

Three genes encoding alpha

This gene encodes a member of the peptidase A1 family of aspartic proteases

and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease

CI072 Rabbit Polyclonal Antibody, 50ul Nucleic Acid Amplification IRF1 has been shown toThe protein encoded by this gene plays an important role in the regulation of endosomal trafficking, and has been shown to interact with Rab proteins that are involved in autophagy and endocytic transport. Expansion of a GGGGCC repeat from 2 22 copies to 700 1600 copies in the intronic sequence between alternate 5' exons in transcripts from this gene is associated with 9p linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia)