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AIRE-1 Polyclonal Antibody, 50ul[BT-AP00311] DNA Synthesis EBV infection membrane protein 1

SKU: 62385108741

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AIRE-1 Polyclonal Antibody, 50ul[BT-AP00311] DNA Synthesis EBV infection membrane protein 1AIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and

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Description

EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins

Mutations in MT-CO1 have been associated with Leber's hereditary optic neuropathy (LHON)

The protein encoded by this gene is involved in processes including neurite growth and migration

The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide

AIRE-1 Polyclonal Antibody, 50ul[BT-AP00311] DNA Synthesis EBV infection membrane protein 1AIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and

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