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SHIP2(Phospho-Tyr986/987) Rabbit Polyclonal Antibody, 50ul Gene Editing Alternative splicing of this gene

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SHIP2(Phospho-Tyr986/987) Rabbit Polyclonal Antibody, 50ul Gene Editing Alternative splicing of this geneThe protein encoded by this gene is an SH2 containing 5' inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.

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Description

Alternative splicing of this gene results in seven transcript variants encoding different isoforms

Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain

The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria

gamma (IL2RG)

SHIP2(Phospho-Tyr986/987) Rabbit Polyclonal Antibody, 50ul Gene Editing Alternative splicing of this geneThe protein encoded by this gene is an SH2 containing 5' inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.

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