NBPF5 Polyclonal Antibody, 50ul Capsule Filter Knockout studies in mice exhibit

Knockout studies in mice exhibit neural tube defects and defective cilia| and mutations in this gene are associated with neural tube defects in humans

Down-regulation of this gene has been associated with a variety of human epithelial malignancies

A similar protein in Rat appears to bind the large subunit of RNA polymerase II and provide a link between transcription and pre-mRNA splicing

Multiple transcript variants encoding several different isoforms have been found for APP

NBPF5 Polyclonal Antibody, 50ul Capsule Filter Knockout studies in mice exhibitNBPF5 (neuroblastoma breakpoint family member 5) is a 351 amino acid cytoplasmic protein that is expressed in medulla and brain and belongs to the NBPF family. NBPF5 contains one NBPF domain and is encoded by a gene that maps to human chromosome 1p13. Chromosome 1 spans 260 million base pairs, contains over 3000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease associated genes, including those that are