Histone H3 Polyclonal Antibody, 50ul[BT-AP04093] Cell Culture Mutations in DNAI2 are associated

Mutations in DNAI2 are associated with primary ciliary dyskinesia type 9

The encoded protein acts as a nuclear transcription factor

and a narrow

Nuclear factor kappa B subunit 2 encoded by NFKB2 can function as both a transcriptional activator or repressor depending on its dimerization partner

Histone H3 Polyclonal Antibody, 50ul[BT-AP04093] Cell Culture Mutations in DNAI2 are associatedHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin