Mnk1 Polyclonal Antibody, 100ul[BT-AP05495] Micro Centrifuge Tubes Lipase member I encoded by

Lipase member I encoded by LIPI is a phospholipase that hydrolyzes phosphatidic acid to produce lysophosphatidic acid

The tyrosine kinase non receptor 2 may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc43Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH

Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation

Mnk1 Polyclonal Antibody, 100ul[BT-AP05495] Micro Centrifuge Tubes Lipase member I encoded byMKNK1 (MAP kinase interacting serine threonine kinase 1) encodes a Ser Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C terminal region of eIF4G. Alternatively spliced transcript variants have been noted for MKNK1.