SETBP Rabbit Polyclonal Antibody, 100ul Endonucleases & Exonucleases Diseases associated with SERPINB5 include

Diseases associated with SERPINB5 include mandibular cancer and laryngeal carcinoma

nuclear DNA-binding protein regulates transcription

DVL2 and/or DVL3)

Eukaryotic gene transcription is regulated by sequence-specific transcription factors that bind modular cis acting promoter and enhancer elements

SETBP Rabbit Polyclonal Antibody, 100ul Endonucleases & Exonucleases Diseases associated with SERPINB5 includeThis gene encodes a protein which contains a several motifs including a ski homology region and a SET binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.