Canine Caspase-3, CASP3 ELISA Kit, 96T Capsule Filter It is involved in various

It is involved in various cellular processes

The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system

but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues

and the CENPA-CAD (nucleosome distal) complex

Canine Caspase-3, CASP3 ELISA Kit, 96T Capsule Filter It is involved in variousInvolved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP ribose) polymerase (PARP) at a '216 Asp Gly 217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix loop helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase 6, 7 and 9. Involved in the cleavage of huntingtin.