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FOS Rabbit Polyclonal Antibody, 100ul Organelle Studies Multiple alternatively spliced transcript variants

SKU: 61485213827

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FOS Rabbit Polyclonal Antibody, 100ul Organelle Studies Multiple alternatively spliced transcript variantsNuclear phosphoprotein which forms a tight but non covalently linked complex with the JUN AP 1 transcription factor. In the heterodimer c fos and JUN AP 1 basic regions each seems to interact with symmetrical DNA half sites. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction cell proliferation and differentiation. PTM: Constitutively

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Description

Multiple alternatively spliced transcript variants of CD40 encoding distinct isoforms have been reported

This kinase also contains a Rac interactive binding (CRIB) domain

The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses

As the sequence environment of the 2 potential ATG initiator codons is the same for the other altrnatively spliced isoforms| alternative initiation of translation could also occur on these transcripts

FOS Rabbit Polyclonal Antibody, 100ul Organelle Studies Multiple alternatively spliced transcript variantsNuclear phosphoprotein which forms a tight but non covalently linked complex with the JUN AP 1 transcription factor. In the heterodimer c fos and JUN AP 1 basic regions each seems to interact with symmetrical DNA half sites. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction cell proliferation and differentiation. PTM: Constitutively

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