EphA10 Polyclonal Antibody, 50ul Mechanical Pipette The protein encoded by this

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins

tissue specificity:Highly expressed in placenta and lung

Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN)

The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions

EphA10 Polyclonal Antibody, 50ul Mechanical Pipette The protein encoded by thisEphrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al. 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.