TNNC2 Polyclonal Antibody, 20ul Gene Editing The carboxy-terminal domain of this

The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor

Mutations in this gene have been associated with ataxia-ocular apraxia

Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect

Alternatively spliced transcript variants encoding the distinct isoforms have been described

TNNC2 Polyclonal Antibody, 20ul Gene Editing The carboxy-terminal domain of thisTroponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn I subunit inhibits actomyosin ATPase, the Tn T subunit binds tropomyosin and Tn C, while the Tn C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn C subunit.