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HEN1 Rabbit Polyclonal Antibody, 50ul Thermo Mix This protein is found associated

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HEN1 Rabbit Polyclonal Antibody, 50ul Thermo Mix This protein is found associatedThe helix loop helix (HLH) proteins are a family of putative transcription factors some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080) LYL1 (MIM 151440) E2A (MIM 147141) and SCL (MIM 187040).

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Description

This protein is found associated with endosomal membranes

It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs

Interacts with the C-terminal tail of PRLHR

Loss of function or expression of this gene is associated with decreased apoptosis

HEN1 Rabbit Polyclonal Antibody, 50ul Thermo Mix This protein is found associatedThe helix loop helix (HLH) proteins are a family of putative transcription factors some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080) LYL1 (MIM 151440) E2A (MIM 147141) and SCL (MIM 187040).

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