UBE4A Polyclonal Antibody, 100ul Cellular Function Assays The gene product is responsible

The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome

The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells

Undetectable in other tissues

OTU deubiquitinase

UBE4A Polyclonal Antibody, 100ul Cellular Function Assays The gene product is responsibleUBE4A encodes a member of the U box ubiquitin ligase family. The ubiquitination factor E4A is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants