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RASF5 Rabbit Polyclonal Antibody, 50ul Human Genome Knockout Libraries Tissue-specific isoforms that differ at

RASF5 Rabbit Polyclonal Antibody, 50ul Human Genome Knockout Libraries Tissue-specific isoforms that differ at

Name: RASF5 Rabbit Polyclonal Antibody, 50ul Human Genome Knockout Libraries Tissue-specific isoforms that differ at
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SKU: 611843551
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RASF5 Rabbit Polyclonal Antibody, 50ul Human Genome Knockout Libraries Tissue-specific isoforms that differ atThis gene is a member of the Ras association domain family. It functions as a tumor suppressor and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules and associates with the GTP activated forms of Ras Rap1 and several other Ras like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different

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Description

Tissue-specific isoforms that differ at the N-terminus have been described

and in follicular adenomas

subcellular location:Mainly cytoplasmic

and mutations in this gene have been associated with Liddle syndrome

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