syntenin Rabbit Polyclonal Antibody, 20ul Molecular Biology The protein encoded by this

The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II)| which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation

The encoded protein may play a role in heart development and specification of limb identity

The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al

These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain

syntenin Rabbit Polyclonal Antibody, 20ul Molecular Biology The protein encoded by thisThe protein encoded by this gene was initially identified as a molecule linking syndecan mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic C terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal membrane organization cell adhesion protein trafficking and the activation of transcription factors. The protein is primarily localized to