SCNBA Polyclonal Antibody, 20ul Electrophoresis & Labeling Co-transcription of this gene and

Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2)

Expression is slightly down-regulated by dexamethasone and slightly up-regulated by IL-10

such as the placenta and testis

This gene encodes a member of the peptidase T1A family| that is a 20S core alpha subunit

SCNBA Polyclonal Antibody, 20ul Electrophoresis & Labeling Co-transcription of this gene andVoltage gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of