ALX3 Polyclonal Antibody, 100ul Isothermal Amplification Induces translational repression through 28S

Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress

IQ calmodulin-binding motif-containing protein 1 has a central coiled-coil region and two calmodulin-binding IQ domains

The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma

Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas

ALX3 Polyclonal Antibody, 100ul Isothermal Amplification Induces translational repression through 28SALX3 encodes a nuclear protein (ALX homeobox 3) with a homeobox DNA binding domain that functions as a transcriptional regulator involved in cell type differentiation and development. Preferential methylation of this gene's promoter is associated with advanced stage neuroblastoma tumors.