PACS1 Polyclonal Antibody, 20ul Digital Burette The isoforms lacking the transmembrane
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PACS1 Polyclonal Antibody, 20ul Digital Burette The isoforms lacking the transmembraneThis gene encodes a protein with a putative role in the localization of trans Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV 1 Nef mediated downregulation of cell surface MHC I molecules to the TGN, thereby
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