REV1 Polyclonal Antibody, 20ul Vessels E3 ubiquitin-protein ligase that may

E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation

overexpression is cytotoxic

and has RNA chaperone activity that may be involved in template switch

|tissue specificity:Expressed in umbilical vein endothelial cells and several cancer cell lines (at protein level)

REV1 Polyclonal Antibody, 20ul Vessels E3 ubiquitin-protein ligase that mayThis gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein protein interactions. A suggested role for the human Rev1 like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA.