Maf1 Polyclonal Antibody, 100ul Cell Transfection The integrin subunit alpha 2

The integrin subunit alpha 2 forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix

Mutations in OCRL cause oculocerebrorenal syndrome of Lowe and also Dent disease

Interacts with KRT17 (By similarity)

When administered after 6-OHDA-lesioning

Maf1 Polyclonal Antibody, 100ul Cell Transfection The integrin subunit alpha 2MAF1 (MAF1 homolog, negative regulator of RNA polymerase III) encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1 dependent repression.