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MAGB4 Polyclonal Antibody, 20ul Shaker&Mixing The encoded protein is predicted

SKU: 59696632086

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MAGB4 Polyclonal Antibody, 20ul Shaker&Mixing The encoded protein is predictedThis gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEB genes are clustered on

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Description

The encoded protein is predicted to contain 6 to 10 transmembrane domains| and a leucine zipper motif in transmembrane domain III

which bind to one another in a homophilic manner

and is located within the NIDDM1 region

Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E)

MAGB4 Polyclonal Antibody, 20ul Shaker&Mixing The encoded protein is predictedThis gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEB genes are clustered on

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