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Phospho-CD32 (Y292) Polyclonal Antibody, 20ul In vitro Assessment A-kinase anchor proteins are scaffold

SKU: 59604863451

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Phospho-CD32 (Y292) Polyclonal Antibody, 20ul In vitro Assessment A-kinase anchor proteins are scaffoldThe Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

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Description

A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations

and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS

which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum

and a mitogen

Phospho-CD32 (Y292) Polyclonal Antibody, 20ul In vitro Assessment A-kinase anchor proteins are scaffoldThe Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

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