p57(Phospho Thr310) Polyclonal Antibody, 50ul Plasma Mutations in this gene are

Mutations in this gene are associated with dilated cardiomyopathy

The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A

As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme

of which the most well-characterized category is represented by the HOX genes

p57(Phospho Thr310) Polyclonal Antibody, 50ul Plasma Mutations in this gene areThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.