SPG16 Rabbit Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection Mutations in DOK7 are a

Mutations in DOK7 are a cause of familial limb-girdle myasthenia autosomal recessive

and is thought to function predominantly in early hematopoietic development

Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA

and are potentially useful targets in cancer vaccine-based immunotherapy

SPG16 Rabbit Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection Mutations in DOK7 are aCilia and flagella are comprised of a microtubular backbone the axoneme which is organized by the basal body and surrounded by plasma membrane. SPAG16 encodes 2 major proteins that associate with the axoneme of sperm tail and the nucleus of postmeiotic germ cells respectively (Zhang et al. 2007