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NDUAB Polyclonal Antibody, 50ul Pathway and Network Analysis Along with the pyruvate dehydrogenase

SKU: 58345625709

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NDUAB Polyclonal Antibody, 50ul Pathway and Network Analysis Along with the pyruvate dehydrogenaseThis gene encodes a subunit of the membrane bound mitochondrial complex I. Complex I is composed of numerous subunits and functions as the NADH ubiquinol reductase of the mitochondrial electron transport chain. Mutations in this gene are associated with severe mitochondrial complex I deficiency. Alternate splicing results in multiple transcript variants.

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Description

Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases

Triggering receptor expressed on myeloid cells 1 amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines

Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b

This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone

NDUAB Polyclonal Antibody, 50ul Pathway and Network Analysis Along with the pyruvate dehydrogenaseThis gene encodes a subunit of the membrane bound mitochondrial complex I. Complex I is composed of numerous subunits and functions as the NADH ubiquinol reductase of the mitochondrial electron transport chain. Mutations in this gene are associated with severe mitochondrial complex I deficiency. Alternate splicing results in multiple transcript variants.

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