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AR Polyclonal Antibody, 100ul[BT-AP14284] Nucleic Acid Isolation & Purification Defects in this gene are

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AR Polyclonal Antibody, 100ul[BT-AP14284] Nucleic Acid Isolation & Purification Defects in this gene areThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This

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Description

Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2

which is also called TKB (tyrosine kinase binding) domain

Belongs to the amino acid-polyamine-organocation (APC) superfamily

Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog

AR Polyclonal Antibody, 100ul[BT-AP14284] Nucleic Acid Isolation & Purification Defects in this gene areThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This

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