KLOTB Polyclonal Antibody, 100ul Insect Expression LGR6 encodes a member of

LGR6 encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily

This protein exhibits GEP activity in vitro with ARF1 and ARF5| but is inactive with ARF6

and redistributes to the region of the spindle poles during mitosis

a single transmembrane segment and two tandem intracytoplasmic catalytic domains

KLOTB Polyclonal Antibody, 100ul Insect Expression LGR6 encodes a member ofContains 2 glycosyl hydrolase 1 regions. However, the first region lacks the essential Glu active site residue at position 241, and the second one lacks the essential Glu active site residue at position 889. These domains are therefore predicted to be inactive.,Contributes to the transcriptional repression of cholesterol 7 alpha hydroxylase (CYP7A1), the rate limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the