LRP1 Polyclonal Antibody, 20ul Site-directed Mutagenesis and gamma subunits that assemble

and gamma subunits that assemble through a coiled-coil domain

see MIM 164011) through BCL10 (MIM 603517) (Wang et al

Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm

This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression

LRP1 Polyclonal Antibody, 20ul Site-directed Mutagenesis and gamma subunits that assembleLRP1 encodes a member of the low density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2 macroglobulin