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CD63 Polyclonal Antibody, 50ul[BT-AP02078] Cell Screening and Imaging This enzymatic action regulates gene
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CD63 Polyclonal Antibody, 50ul[BT-AP02078] Cell Screening and Imaging This enzymatic action regulates geneCOL25A1 (collagen type XXV alpha 1 chain) encodes a brain specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over expression of this collagen in mice, however, found changes in pathology
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