RPB3 Polyclonal Antibody, 50ul Molecular Sciences Mutations in this gene are

Mutations in this gene are associated with type 1 elliptocytosis (EL1)

inhibition of renin and aldosterone secretion

This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation

fragile X syndrome and myotonic dystrophy

RPB3 Polyclonal Antibody, 50ul Molecular Sciences Mutations in this gene areThis gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21.