SC65 Polyclonal Antibody, 20ul Low-speed Centrifuges Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding different isoforms have been described for MED23

a childhood-onset neurodegenerative disease characterized by demyelination of motor and sensory neurons

It interacts in a complex with chromatin modifying factors

Expression of SERPINB7 is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma

SC65 Polyclonal Antibody, 20ul Low-speed Centrifuges Several alternatively spliced transcript variantsThis nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes.