EGFR Polyclonal Antibody, 100ul[BT-AP15380] Glassware Alternative promoter usage and splicing

Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2

suggesting its role in promoting neuritogenesis

and vertebrates contain classes 3-7

SMAD family member 1 encoded by SMAD1 belongs to the SMAD

EGFR Polyclonal Antibody, 100ul[BT-AP15380] Glassware Alternative promoter usage and splicingThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.