Arrestin-C Polyclonal Antibody, 50ul Lentiviral Packaging is related to mutations in

is related to mutations in the ALMS1 gene

It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand

The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria

also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity

Arrestin-C Polyclonal Antibody, 50ul Lentiviral Packaging is related to mutations inThe protein encoded by ARR3 is a non visual arrestin which binds to agonist activated, phosphorylated G protein coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma tubulin to help regulate proper centrosome function.