SLAF7 Polyclonal Antibody, 100ul Cell Transfection Homozygous mutations at highly conserved

Homozygous mutations at highly conserved position of RAD54B were observed in human primary lymphoma and colon cancer

it is localized to the mitochondria

Does not affect the proliferation of cancer cells in vitro

and this protein is 99% identical to the mouse

SLAF7 Polyclonal Antibody, 100ul Cell Transfection Homozygous mutations at highly conservedIsoform 1 mediates NK cell activation through a SAP independent extracellular signal regulated ERK mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro).,Contains 1 Ig like C2 type (immunoglobulin like) domain.,tissue specificity: Expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow,