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Rb(Phospho Ser807) Polyclonal Antibody, 20ul Primary Antibodies Gene expression is high during

SKU: 55510002811

4.4
PLN97.20 PLN120.20

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Rb(Phospho Ser807) Polyclonal Antibody, 20ul Primary Antibodies Gene expression is high duringThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

Gene expression is high during fetal development and in most tumors

The product of GABRE belongs to the ligand-gated ionic channel (TC 1

although not all variants have had their full-length sequences determined

It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation

Rb(Phospho Ser807) Polyclonal Antibody, 20ul Primary Antibodies Gene expression is high duringThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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