Phospho-Akt1 (S129) Polyclonal Antibody, 100ul Variant Libraries This protein belongs to the

This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood

Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer

form a heterotetrameric complex called an adaptor

the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1)

Phospho-Akt1 (S129) Polyclonal Antibody, 100ul Variant Libraries This protein belongs to theThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a