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HNF6 Polyclonal Antibody, 50ul Sealing Film Mutations in this gene or

SKU: 54896927561

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PLN162.00 PLN197.00

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HNF6 Polyclonal Antibody, 50ul Sealing Film Mutations in this gene orThis gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver expressed genes, and antagonizes glucocorticoid stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple

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Description

Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly

Upregulated expression of this gene in astroglial cells upon exposure to lipopolysaccharides suggests a function for the encoded protein in the brain

The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1

As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments

HNF6 Polyclonal Antibody, 50ul Sealing Film Mutations in this gene orThis gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver expressed genes, and antagonizes glucocorticoid stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple

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