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LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 50ul Dry Bath The encoded protein exhibits GEP

SKU: 54601300029

4.4
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LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 50ul Dry Bath The encoded protein exhibits GEPThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative

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Description

The encoded protein exhibits GEP activity in vitro with ARF1| ARF3| and ARF6 and is 83% homologous to CYTH1

3'-diiodothyronine (T2)

providing a protective effect against chemotherapy-induced adverse effects

Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles

LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 50ul Dry Bath The encoded protein exhibits GEPThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative

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