Topo IIIBeta-1 Polyclonal Antibody, 50ul Micro Centrifuge Tubes MIM 187410)| a DNA polymerase

MIM 187410)| a DNA polymerase that catalyzes the polymerization of DNA in the absence of a DNA template (Yamashita et al

The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase| which may mediate insulin signals to the actin cytoskeleton

Belongs to the EBP2 family

Mutations in this gene are associated with congenital stationary night blindness type 2B

Topo IIIBeta-1 Polyclonal Antibody, 50ul Micro Centrifuge Tubes MIM 187410)| a DNA polymeraseTOP3B encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome